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The most prominent factor is aneuploidy (e.g., strikingly increasing trisomy 21), indicating that ova quality decreases with age.
More strikingly, increasing the number of correlated covariates also affected the true positive rate, which decreased with almost all methods (see Additional file 1).
Because most cancer rates in the general population increase substantially with increasing age, even steady or declining RRs with increasing age can be associated with strikingly increasing EARs, such as the pattern described above for breast cancer after HL [20].
Notably, not only have psychostimulants been suggested to be effective for ADHD-like symptoms in autism spectrum disorder individuals, but the prevalence rates of their use in autism are also strikingly increasing (Dalsgaard et al., 2013).
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The practice continued under Mayor David N. Dinkins in the early 1990's, and strikingly increased under Mayor Giuliani, whose administration struck deals providing more than $2 billion in benefits to more than 50 companies, including Merrill Lynch, Credit Suisse First Boston, Travelers and The New York Times.
However, it strikingly increased FCR activity compared with EDTA-Fe treatment.
The number of people undergoing facial filler injections to get a youthful twinkle has strikingly increased in the last decade.
The effects of the activation overwhelmed that of the inhibition, thus the flux of GPI strikingly increased 50% on Glc/Glu.
We recently demonstrated that addition of the central DNA flap of HIV-1 to an HIV-derived lentiviral vector strikingly increases transduction of CD34+ cells.
H2 evolution was reduced by 78%, and the total alcohol yield was strikingly increased by 19% to 0.44 g/g glucose, much higher than those yet reported for butanol fermentation.
Moreover, the occurrence of duplication of the targeted chromosome was strikingly increased in the exo1Δ sgs1Δ double mutant but not in the respective single mutants demonstrating that the Exo1 and Sgs1 proteins independently suppress whole chromosome duplication during gene targeting.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com