Exact(5)
On the other hand, when the NAC was co-cultured side-by-side with normal animal cap (ectoderm), the EB3 in the NAC cells moved toward the boundary between the two explants with strikingly biased movement (Fig. 4b), reminiscent of the boundary-contacting cells in the Keller explants (Fig. 2a).
HAR1 and HAR2 (HACNS1), the two fastest evolving HARs, have strikingly biased substitution patterns.
In addition, though, the drop in heterozygosity in Maxxa is strikingly biased with respect to genome, such that for the AT genome only a single heterozygous locus was detected.
Most of these genes show strikingly biased expression patterns in which expression is dominated by a single homoeolocus.
This affirmation is consistent with the strikingly biased distribution of SIDERs within 3'UTRs (Table 1), as confirmed with recently published computational tools [ 35].
Similar(55)
We find strikingly large biases in natives' perceptions of the number and characteristics of immigrants: in all countries, respondents greatly overestimate the total number of immigrants, think immigrants are culturally and religiously more distant from them, and are economically weaker -- less educated, more unemployed, poorer, and more reliant on government transfers -- than is the case.
Consequently, nPTB and ROD1 have a very distinctive codon composition, with a high frequency of codons ending in A or T, while PTB has a much higher proportion of codons ending in G or C. Strikingly, codon bias in the human genome shows an overall preference for G or C in the third codon position (∼59%) [33].
We observed little evidence for such a positive correlation; however, plots of siRNA versus total RNA abundance for single-copy and multi-copy loci showed strikingly different distributions, with multi-copy loci clearly biased towards higher siRNA production.
Thus, in the tumor microenvironment where immune checkpoint molecules are highly expressed, the balance of co-signals is greatly biased toward the inhibition-dominant side, so that anti-tumor responses are strikingly restrained (Fig. 3a).
Strikingly similar results were obtained for D. melanogaster, in which highly expressed and highly biased genes were represented in only one of the five clusters identified (group 4; Figure 5B).
While currently available information is highly biased and only covers a relatively small portion of the proteome, our systematic map appears strikingly more homogeneous, revealing a "broader" human interactome network than currently appreciated.
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