They showed that the AmmVIII toxin of the Androctonus mauretanicus mauretanicus scorpion venom, which is 87% analogues to AahII but with a striking different C-terminal end, is totally devoid of toxicity.
We note that mbl-1 null mutants display a particularly striking and reproducible terminal dendrite branching defect.
These differences were most striking for C-terminal 1 50 (especially 1 25) positions (Additional file 4: Figure S2).
In addition to a pronounced hook within the protein's C-terminal half, a striking feature is a "nose" at the N-terminal end, a morphology generated by a pair of anti-parallel helices that are about twice as long as their neighbors.
In striking contrast, the C-terminal region, coding for the mature peptide, is often highly divergent from species to species.
We suggest, therefore, that the wild type-like transcript is expressed mainly or exclusively in cone photoreceptors, accounting for the relative sparing of cone transmission as seen in the optokinetic response, and that the mutant transcript is expressed mainly or exclusively in rod photoreceptors, accounting for the striking loss of synaptic terminals and consequent thinning in the OPL.
The alignment of the RpoT polymerases from N. advena with those from Arabidopsis, Physcomitrella and Selaginella (see Figure 2) demonstrates a high degree of conservation at the amino acid sequence level, most striking in the C-terminal part, including all functionally crucial regions and residues known from the phage T7 RNA polymerase [ 28, 29].
Mr. Calatrava has produced such a striking design for the PATH terminal that it almost appears as if there could be too many distinctive buildings on one intersection.
In October, JetBlue opened a striking new food court in Terminal 5 of Kennedy Airport in New York (more on that later), and with another holiday season approaching, it seemed appropriate to see if good restaurants might exist in other American airports, perhaps overshadowed by the Cinnabons and Sbarros but producing honest, edible food nonetheless.
However, little is known about consumer preferences regarding the design of passenger areas, which is striking as the design of terminal buildings affects consumers' emotional state and shopping behaviour.
The most striking feature of the C-terminal domain of eRF1/Dom34p is the GILRY motif (positions 441 445, fig. 1B) implicated in eRF1 eRF3 complex formation [ 11].
