Sentence examples for striking reduction of from inspiring English sources
We report a striking reduction of α-GalCer-induced iNKT cell activation by monocyte derived dendritic cells (moDC) upon their exposure to NBP during maturation.
In one in vitro study, Hh inhibition with cyclopamine resulted in down-regulation of Snail and up-regulation of E-cadherin, as well as a striking reduction of invasive capacity.
It is noteworthy that the valance band position of Cu2O is higher than Au (5.1 eV), Ag (4.2 eV) and also aligned with the highest occupied molecular orbital (HOMO) levels of BPEA (5.49 eV) [30] and TIPS-PEN (5.34 eV) [47], leading to a striking reduction of the hole-injection barrier and consequently the lower contact resistance.
Interestingly, the S-alkylated mercaptotriazole 8b and the 1,3,4-oxadiazole 9 produced striking reduction of serum levels of total cholesterol (TC), triglycerides (TGs) and low-density lipoproteins (LDLs) and elevation of serum high-density lipoproteins (HDLs) being more active than the reference gemfibrozil.
Furthermore, we observed a striking reduction of inflammatory molecules in the treated group.
After only 48h of erlotinib treatment we observed a striking reduction of [18F]FLT uptake in the sensitive cell lines HCC827 and PC9.
Accordingly, when we analyzed the seedling development, in CP 72 transgenic line, we detected striking reductions of growth in the aerial parts of the MOF-induced CP 72 transgenic line in comparison with the seedlings that were treated with water.
Because of the apparent striking reductions of β7 integrin expression on CD27negative B-cells after incubation with epratuzumab, and the known interdependence between β1 and β7 integrin expression on human T-cells which share the α4 integrin subunit [ 27], the regulation of β1 integrin expression after epratuzumab incubation was investigated.
Western blotting of third instar larval brain extracts confirmed a striking reduction in levels of both FMRP::GFP and endogenous FMRP in the absence of BicD.
Our initial experiment using metronomic topotecan showed a striking reduction in size of primary tumours and also of metastatic spread, after oral metronomic topotecan administration.
Finally, a recent genome-wide transcriptional profiling study of dnj-14 mutants revealed a striking reduction in expression of ubiquitin proteasome system (UPS -related genes in comparison to wild type control strains [76].
