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The book details Maeda's theory that physical combat could be broken down into distinct phases, such as the striking phase, the grappling phase, the ground phase, and so on.
When we attempted, however, to lower the concentration of the Nup98 FG domain, we observed a striking phase separation into a protein-rich and a protein-poor phase.
This point is potentially relevant in the context of somitogenesis, where a frequency gradient is thought to underlie the striking phase waves that traverse the rostro-caudal axis.
Striking phase 2 results were obtained for triple therapy including the NI sofosbuvir, which resulted in 90% SVR in treatment-naïve HCV genotype 1 patients, and even higher in genotype 2 and 3 patients, after only 12 weeks of treatment (Kowdley et al, 2013a; Lawitz et al, 2013a).
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The migratory locust, Locusta migratoria manilensis, undergoes a striking behavioral phase transition, from a solitary, essentially harmless animal to a seemingly endless cloud of voracious, traveling swarms that devour the vegetation in their path.
Symptomatic CAPS is accompanied by a striking acute-phase response, with serum concentrations of C-reactive protein (CRP) and serum amyloid A protein (SAA) frequently elevated by 100- to 1,000-fold 1,000-foldg the high risk of AA amyloidosis [ 10, 12].
In a study which analyzed the effect of DON upon the cell cycle distribution, it was found that this drug causes a striking S-phase block with concurrent increase in G1 and G2-M populations.
It constitutes a striking example of partial phase state and provides a route to a new phase state.
As the most striking result during stationary phase, however, we obtained in the 6S RNA deficient strain a concerted expression reduction of genes constituting the translational apparatus.
Most striking during the persistent phase was the upregulation of genes encoding CCL5/RANTES, CCL7/MCP-3, CCL8/MCP-2 and CXCL9/MIG, which are involved in chemoattraction of T cells (Liao et al, 1995; Loetscher et al, 1994).
In light of the striking results of this phase I study, an expansion cohort trial including 180 ALK-rearranged NSCLC receiving ceritinib at the recommended dose (750 mg/day) has been reported at the 2014 American Society of Clinical Oncology ASCOO) Annual Meeting and the results were promising [ 57].
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CEO of Professional Science Editing for Scientists @ prosciediting.com