Sentence examples for striking mutation from inspiring English sources

A striking mutation, R231W corresponding to the second basic residue completely disrupts channel closure by producing instantaneous and voltage-independent K+ currents (Figure 2E and F).

A striking mutation, R231W corresponding to the second arginine in S4 completely disrupts channel closure, producing instantaneous and voltage-independent leak K+ currents whose modulation by KCNE1 is disrupted.

This evolutionary history together with the striking mutation patterns is indicative of a putative neofunctionalization event that took place late during AR-B evolution It is tempting to link this neofunctionalization event to the plasticity of sex determination in Percomorphs.

Mining available genome-wide resequencing data for 50 BBC sires (data not shown), did not reveal any striking mutation associated with the AHAP9 haplotype that might underlie the QTL.

The analysis of nsSNPs showed that striking mutations are more frequently found between two Miscanthus species than between Miscanthus and sorghum, reflect that Miscanthus seems to be more tolerant of point mutations than sorghum.

This may be a consequence of the much higher level of gene duplication in Miscanthus, in which striking mutations may be better tolerated by virtue of the presence of a second gene copy that may confer essential functionality.

The impacts on gene function of SNPs that differ between the two Miscanthus species are significantly more positive than SNPs between sorghum and Miscanthus (t statistics = 125.37, P = 0), indicating that striking mutations are more frequently found between two Miscanthus species than sorghum and Miscanthus.

The impacts of striking mutations found by nsSNPs were much lower between sorghum and Miscanthus than those between the two Miscanthus species, perhaps as a consequence of the much higher level of gene duplication in Miscanthus and resulting ability to buffer essential functions against disturbance.

Even more striking are mutations in the linker helix RING1 interface.

This striking increase in mutation rate was due to acquiring a mutator phenotype during the latter period [ 13].

Neighboring nucleotides exert a striking influence on mutation, with the hypermutability of CpG dinucleotides in many genomes being an exemplar.