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Tracing early coronary sprouts revealed a surprisingly striking inheritance pattern in the ventricular septum.
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The striking parent-of-origin inheritance pattern of SDHD-linked tumors in man strongly suggests the involvement of an imprinted locus in paragangliomas.
The first striking result is that the inheritance of heteroplasmic groups produces the same heteroplasmy variance as binomial partitioning, regardless of cluster size.
The most striking evidence for transgenerational epigenetic inheritance in the mouse comes from experiments studying the Agouti (A) locus, a determinant of coat colour (Morgan et al., 1999).
The most striking observation on prion-mediated epigenetic inheritance is that it can be turned into prion-independent genetic inheritance with a relative ease, a phenomenon denoted genetic assimilation of an epigenetically inherited trait.
SDHD-linked paragangliomas in man show a striking 'imprinted' or parent-of-origin inheritance [4] and we have proposed a model including a maternally-expressed imprinted gene on chromosome 11 in SDHD tumorigenesis [6].
It is striking that we found both reversed TL inheritance and reversed TL sex- specificity in kakapo compared to human.
We bring together AD and AMD case control data and observe that not only is CST3 associated with both diseases but there is a striking similarity in the underlying model of inheritance, namely a recessive genetic model.
Bioinformatic analysis has indicated a striking overlap between genes relevant to transgenerational epigenetic inheritance and the contents of exosomes released by a variety of cells, including cancer cells [ 24, 50– 50].
The result was striking: the risk of schizophrenia correlated powerfully with the inheritance of the C4 gene variant — particularly C4A.
More striking, the revenues of companies run by entrepreneurs who received bigger inheritances grew 20% faster.
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