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HC was first designated by Sjaastad and Spierings [8] as a unilateral headache strictly responsive to indomethacin.
In contrast, our IbNAC is strictly responsive to both wounding stresses (MW or HA) involved in both JA - and SA signaling pathways, which suggests it is a positive transcriptional activator for regulating sporamin gene expression and partially other downstream genes (e.g. PR).
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Table 1 International Headache Society diagnostic criteria for hemicrania continua Description: persistent strictly unilateral headache responsive to indomethacin Diagnostic criteria A.
Thus MTT1 is not strictly a heavy metal-responsive protein, but is induced under more general stress conditions.
Hemicrania continua (HC) is a strictly unilateral, continuous headache that is exquisitely responsive to Indomethacin [1].
Hemicrania Continua (HC) is a strictly unilateral continuous headache that is exquisitely responsive to Indometacin but some patients cannot tolerate this drug.
Indeed, the differential expression of 16 H2O2-responsive genes was found to strictly depend on the presence of iron, whereas the expression of 15 genes was only affected under iron-restricted conditions.
Indeed, this correspondent has also seen strictly lateralized headache that swaps sides and is not indomethacin responsive: which is the greater feature with which to classify such cases?
The intracellular zinc homeostasis is generally strictly controlled, and in C. albicans, the response to zinc deficiency is mediated by the transcription factor Csr1 (Candida suppressor of ROK1) (11), the ortholog of Saccharomyces cerevisiae Zap1 (zinc-responsive activator protein).
This analysis allowed the identification of 57 genes encoding for proteins strictly associated with ER function, in control and stress conditions, and 59 UPR responsive genes, encoding for proteins regulating survival, cell death and other cellular processes indicated as miscellaneous.
Reversible inactivation of Glo1 was observed upon exposure of cells to extra-cellular nitric oxide (NO) which was strictly dependent on the level of GSH indicating that Glo1 is an NO-responsive protein [15], [16].
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