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Plant TPX2 genes in general are duplicating liberally while M20L genes are apparently strictly resistant to duplications.
That the expression of the above proteins was only affected to the same extent in resistant compared to parental cells when the resistant cells were treated with 3 times more drug than parental cells (see Fig. 3) suggests that resistant cells are not strictly "resistant" to SINE compounds but rather are less sensitive.
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Bianca has been reported to react to P. viticola contact with a hypersensitive reaction (HR) leading to cell death in the proximity of infection sites, which constitutes a common phenotype strictly associated with resistant genotypes [ 20].
However, gram-positive cocci that are strictly aerobic, oxacillin-resistant, and arginine dihydrolase-positive should be recognized as potential Kytococcus species and taken into account when endocarditis is suspected.
Transformed plants were obtained by selecting on kanamycin-resistant medium strictly and regenerated.
Nevertheless, presence of prion infectivity does not strictly correlate with PK-resistant PrPSc load and protease-sensitive PrPSc species harbor significant amounts of prion infectivity [ 38].
Since the first degree relatives are hyperinsulinemic they are most likely insulin resistant in a strictly molecular sense although not physiologically.
The patients could not strictly be described as treatment resistant and so comparison with the initial phase patients in STAR-D may be appropriate.
In this context, it is worth pointing out that even one of the most dreaded imatinib-resistant mutants of Bcr/Abl Bcr/Ablp210T315I remains strictly dependent on Stat5.
Pathogens that were initially strictly hospital-acquired, such as methicillin-resistant Staphylococcus aureus (MRSA), became community pathogens (CA-MRSA) and even zoonotic pathogens with the emergence of livestock-associated (LA -MRSA, thereby totaLA -MRSAging therebydemiology of MRSA.
In conclusion, our experience supports the view that in immunocompromised patients with persistent infection, emergence of resistant viral strains should be strictly monitored.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com