Although vinflunine was efficacious in the randomized phase III trial, patients under study conditions may not fully reflect actual clinical practice as they are selected and their therapy management is strictly protocol-driven.
Care group B, podiatrist Another interviewee explained how strictly protocol-based care provision led to a one-size-fits-all approach to care delivery, which in turn, stood in the way of high quality, person-centred care: "If you have a meat chopper and you put meat in it, it doesn't matter what you put in it, you will always get minced meat.
A total of 485 patients (71.9%) were staged and treated strictly per protocol (PP), while 115 (17%) and 75 patients (11.1%) had major or minor protocol violations, respectively.
It had been alleged that two members of the England coaching team approached match officials in the tunnel at Twickenham at half-time during the 33-13 loss to Australia which is strictly against protocol.
"The Chinese naval vessel strictly followed protocol and handled the incident," it said.
The rigid, strictly applied protocol that Alura enforces on Violet is essential to the smooth functioning of their sub-dom relationship that exists from 9 AM until 6 PM, five days a week.
However, to be effective, the analysis of mitotic activity must be carried out by well-trained personnel, using a strictly defined protocol [16], [19].
Residential exposure to eight a priori selected components of particulate matter (PM) was characterized following a strictly standardized protocol.
At the initial drug dispensing stage, patients are advised to strictly follow protocol instructions, which will be reiterated at each study visit.
To our knowledge, the epidemiology and outcomes of VAP have not been evaluated in ARDS patients receiving a strictly standardized protocol of lung-protective mechanical ventilation [ 12].
Further research is needed to investigate the mechanisms of differences in cancer survival between countries, by comparing distribution of stage at diagnosis and treatment, based on a strictly controlled protocol, as implemented by some international collaborative studies.
