In contrast, a large computational domain is preferred to strictly predict transitions in the aerosol concentration and size distribution from sources of aerosol-particle formation.
Recently, it has been reported that the amplification of ACTN4 can strictly predict the clinical outcome, and ACTN4 has been recognized as an oncogene 6, 11, 13.
Especially, Noro et al. reported that ACTN4 amplification could more strictly predict poor outcome than actinin-4 protein expression in stage-I adenocarcinoma of the lung 13.
Our RD analysis however indicates that the achievable rate-region of SP-DKLT codes for jointly Gaussian sources is strictly inside that predicted by the DKLT of [8].
Since activation and repression can be mediated by distinct co-factors and binding sites [34], we concentrated strictly on targets predicted to be activated by the TF; these constitute the majority of the interactions in the reverse-engineered regulatory network and extension to repressed subsets is straightforward.
Proteomics is particularly well suited for the analysis of the microenvironment, given the host origin of numerous components of the microenvironment that lack discernible genomic alterations, and given the contribution of protein release and shedding of proteins from the surface of cancer cells that cannot be predicted strictly from genomic analysis.
Signature residues for the entire Epd family, such as the four strictly conserved Cys, are predicted to be critical for the common biological function of all Epd genes.
We find that epiallelic reversion, recombination, parent-of-origin effects, and transgressive segregation are key parameters in these populations: Their joint effects can produce complex and highly dynamic inheritance patterns that cannot be predicted from strictly Mendelian models.
For a dominant trait with no imprinting (k 1 = k 2 = k ≠ 0 ) the true response to selection (31) is strictly less than that predicted by the breeder's equation (35).
The second and partially related problem is that the potential temporal instability of epigenetic variation can produce a level of phenotypic dynamics at the population-level that cannot be predicted from strictly Mendelian models of inheritance.
