The extra X chromosome in Klinefelter individuals forces the cell not only to strictly apply the rule of X inactivation, but also to face the interference of additional genes that escape from inactivation on the additional chromosome.
A gracious but competitive host, Heskin applied rules strictly but was generous in appreciating others' good play.
"The prevailing view in Europe is that these guys are crazy," says a senior official involved in talks with the Greeks, "and that the only thing that will bring them to their senses is a near-death experience".The different treatment of Greece and France shows that the question of whether, and how strictly, to apply rules is highly political.
Georgiou's crime was that back in 2009, he strictly applied globally accepted international rules in reporting the Greek government's budget deficit, which had the effect of increasing it by just under 3% to a whopping 15% of GDP.
The 2011 Guéant memorandum, which directed prefectures to strictly apply immigration rules to foreign post-secondary graduates, was overturned May 31, almost exactly a year after it was first announced.
He concluded that military police guards at the detention center "knew, were following and strictly applying" proper rules on the use of force, documents showed, and he cited a "conflict between obtaining accurate, timely information and treating detainees humanely". Senior officials at the Criminal Investigation Command's headquarters took a different view.
In a report published Aug. 24 in the journal Physical Review Letters, Dr. David A. Meyer of the University of California at San Diego and Dr. Thad A. Brown of the University of Missouri presented formal proof that collective decisions can be chaotic, even when the views of all participants are known and a standard voting rule is strictly applied.
On July 7th shares in Freddie Mac and Fannie Mae, the American housing-finance giants, were pummelled on account of a Lehman Brothers report which suggested, if accounting rules were strictly applied, that the government-backed firms would have to raise $75 billion between them.
Formally, Momentum obliges all its members to also be Labour party members, under a rule change made last year in part to prevent it being infiltrated by far-left groups, but in practice the rule is not strictly applied.
Nasonia lacks chromosomal sex determination, so Haldane's rule cannot be strictly applied in this system.
However, this rule cannot be strictly applied for systems which contain steric stabilizers (e.g., surfactants or polymers with high HLB value), because its adsorption will decrease the zeta potential due the shift in the shear plane of the particle [ 21].
