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Discover Ludwig'strict specificity' is a correct and usable phrase in written English
You can use it to refer to a very precise and exact way of doing something. For example, "In order to ensure accuracy, we must adhere to a strict specificity throughout the project."
Exact(44)
Platypus is an exception however, being the only animal found to have conserved Gly193 in KLK10, probably indicating that this mutation was later introduced in order for the protein to acquire a very strict specificity and likely a highly specific biological function.
After overexpression in Saccharomyces cerevisiae, VfCBR1A was enzymatically active, and like its Arabidopsis ortholog, displayed strict specificity for NADH as the reductant.
Upon cytidine binding, a large induced fit was observed at the uridine/cytidine binding site, which endows UCK with a strict specificity for pyrimidine ribonucleosides.
Inhibitors that show strict specificity for one protease usually achieve this selectivity by combining substrate-like binding in the active site with exosite binding on the protease surface.
Alliinase shows a strict specificity toward alliin except that onion root isoforms, which are different in glycosylation, exhibit an additional activity toward L-cystine to a limited extent (Lancaster et al. 2000).
Protein extraction using sodium dodecyl sulfate and 2-mercaptoethanol ensured strict specificity of the ELISA, and components of three popular processed foods had no effect on the ELISA response.
Similar(16)
Many parasites have evolved strict specificities to particular hosts.
These reactions are normally carried out by the unrelated proteins MetA (homoserine O-succinyltransferase) and MetX (homoserine O-acetyltransferase), however the two proteins do not have strict specificities [ 12].
Therefore, we sought to solve the crystal structure of the light chain of medaka enteropeptidase (MEPL), and gain insights into the determinants for its stricter specificity.
However, in secondary structure, the active centers do not show any obvious differences between the two enzymes, which intimates that the stricter specificity of MEPL may depend on the distinct amino acid sequence and unique intramolecular interactions.
Legumain-like proteases are members of the cystein peptidase family (Clan CD, Family C13) and act specifically as asparaginyl endopeptidases with strict cleavage specificity.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com