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These low mutation rates are ensured by the high fidelity of DNA replication due to the strict selectivity of correct bases and the proofreading function of DNA polymerases, as well as the mismatch repair system.
The rather strict selectivity of the originally investigated class I basidiomycete CDHs for cellodextrins and lactose [ 60, 84] mainly found application in lactose biosensors for the dairy industry [ 55, 58, 85] or cellobiose biosensors that can be used to follow cellulose hydrolysis caused by cellulose-hydrolysing enzymes [ 54, 86].
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The bank's analyst Robert Muir said: "Balfour offers the relative attractions of a legacy of prudent accounting, and strict selectivity on new projects.
Subtypes of various NiCoTs have different ion preferences ranging from strict selectivity for Ni to unbiased transport of both ions to strong preference for Co.
A 12-mer peptide (9) without a thiol group was designed by the hybridization of two NPR3-binding peptides: a linear ANP fragment peptide analog and musclin, a murine member of the bHLH family of transcription factors, possessed high binding affinity and strict selectivity for NPR3.
Its strict selectivity for insects has been documented by toxicity, electrophysiological and ligand receptor binding assays.
BotIT6 has been reported to be the most potent toxin from Bot venom that has a strict selectivity for insects.
From a clinical perspective, CSC-targeted therapy should have strict selectivity for CSCs, which is a serious obstacle for most molecular targeted therapies presently used.
"But we do our homework and have a strict selectivity criteria.
His strict selectivity did not keep Mr. Lee from a certain anthropomorphic empathy as he went back to finish culling.
We use a strict cut off criterion for selectivity of the genes based on both the p-values and lods ratio, as proposed in [ 20].
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