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Moreover, studies using strict outcome criteria suggest CFT only achieves remission in around 50% of adolescents [ 6, 8].
However, since it intends to change the occurrence of specified endpoints it is amenable to a strict outcome evaluation.
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AEHS-LS defines a strict outcome-concept structure, such that lessons follow a traditional structure outlining concepts, delivering materials, and then summarizing with a plenary.
The aRR of NSI for oral glucocorticoid exposure in the preceding 45 days using the stricter outcome definition was 1.09 (0.98 to 1.22).
The established associations of autoantibody profiles with clinical subtypes may at least require consideration in the design of SLE trials for defining stricter outcome criteria.
Additional analyses involved a stricter outcome of any increase in total SHS ≥5 (∆SHS ≥5), which delineates the subgroup of patients with rapid radiographic disease progression, also previously examined in the ESPOIR cohort [ 27].
We also examined a stricter outcome definition of chronic kidney disease, defined as eGFR <60 mL/min/1.73m on at least two occasions more than 90 days apart and without any intervening or subsequent eGFR ≥90 mL/min/1.73m, and/or one of 45 diagnostic codes with known positive predictive values over 80% for chronic kidney disease.
Furthermore, we show that engaging in cooperation can be modulated by the motivational state of the animal revealing that environmental factors may impinge on the perception of the strict economic outcome of social interactions.
We assessed the sensitivity of our strict adherence outcome definition by relaxing the requirement for being classified as adherent versus non-adherent.
OTC A (tone L), F, and G were the only hearing aids that could meet the amplification needs of elderly people with presbycusis if a strict fitting outcome criterion was used.
In the sensitivity analyses, we investigated whether effect estimates would change in response to more strict definition of outcome (which combined both diabetes diagnosis and anti-diabetic treatment) and exclusion of patients that were followed less than one year.
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