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The strict occurrence of these two mutations in single AA cases makes difficult the interpretation of these results.
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Nowadays the association of MS with the HLA-DR2 haplotype, comprising the HLA-DRB1*1501 and HLA-DRB5*0101 alleles, is the most replicated result among very different populations and a biological explanation was recently found for the strict co-occurrence of these alleles.
To explain the strict co-occurrence of putative intron loss and gene conversion is, however, more challenging.
For this comparison, we used a stricter keyword occurrence cutoff of 25 or more and also applied relevance scoring to obtain higher specificity in the time analysis.
We investigate whether whole genomic data would provide some clues about genetic adaptations to subterranean habitats, and whether the strict co-occurrence of the karstic landscape and Sinocyclocheilus species might serve to reveal aspects of the biogeographic history of the uplift of the Qinghai-Tibetan Plateau.
The idea consists of updating the controller by the new post-fault system model in first time and; in second time; modifying the set-point or reference according to the system constraints which become more strict after fault occurrence in order to avoid any actuator saturation and ensure system stability.
This relatively high resolution documentation of coeval, yet distinct species in the northern and southern regions of the WIB constitutes robust evidence refuting the hypothesis of strict time-transgressive occurrences of ceratopsid taxa [5].
In this study, we notice a strict correlation between the occurrence of T5SS and the presence of an outer membrane.
The late-19th-century world she portrays in this novel is one in which early death (of parents, of children) is a painful but accepted commonplace, injury and fatal accidents on the job are regular occurrences, and strict regulation of powerful feelings -- both at home and in any respectable social milieu -- is not merely recommended but mandatory.
The inherent complexity of critical production systems, coupled with policies to preserve people's safety and health, environmental management, and the facilities themselves, and stricter laws regarding the occurrence of accidents, are the motivation to the design of Safety Control Systems that leads the mitigation functionality.
The evaluation of clinical tolerance to spontaneous breathing by using exclusively subjective criteria has important drawbacks; on the one hand, strict criteria might increase the occurrence of unnecessarily prolonged mechanical ventilation but, on the other hand, permissive criteria might increase the occurrence of reintubation.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com