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There is reason to conclude that if we wish to discover social contracts that best achieve a set of interrelated normative desiderata (e.g., liberty, equality, welfare, etc)., a deliberative process that draws on a diversity of perspectives will outperform one based on a strict normalization of perspectives (Gaus 2011b).
On admission, patients were randomly assigned to strict normalization of blood glucose levels (80 110 mg/dl) or to a conventional glycemic control (180 220 mg/dl) with the use of sealed envelopes.
The authors randomized 1200 medical ICU patients to strict normalization of blood glucose levels (80 to 110 mg/dL) with the use of insulin infusion or to conventional therapy with a more liberal blood glucose target (180 200 mg/dL).
Van den Berghe et al. (150) reported cost savings of 3,476 USD per patient by strict normalization of BG levels with use of a post hoc health careresourceutilization analysis of their randomized mechanically ventilated surgical ICU patients.
Patients were randomly assigned to strict normalization of blood glucose levels (80 120 mg/dl) with the use of insulin infusion or to glycemic control through glucose-free venous hydration, hypoglycidic nutritional formula and subcutaneous insulin if the blood glucose level was higher than 180 mg/dl in the measurements taken every 6 hours.
A total of 1548 medical and surgical patients were randomised on admission either to a strict normalization of blood sugar to 4.5 6.1 mmol/l, using a continuous infusion of insulin called the 'intensive insulin schedule' (IIS), or to a conventional strategy of treating blood sugar levels above 12.0 mmol/l with the 'restrictive insulin schedule' (RIS).
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Furthermore, our additional normalization of total DA to total TH harvested in the sample is the strictest normalization to DA neuropil and gives the best insight into endogenous TH activity.
From this background list, after a strict data normalization and filtering process, a total of 52 genes were significantly (P<0.05, fold change>1.5) up-regulated and 31 significantly down-regulated (Tables S1 and S2, respectively) in LP vs. CP fetuses.
Note that this could be remedied by changing to "strict" per UT normalization.
In the present study, a parametric framework based on a strict model for normalization is applied to data acquired using several slide-glass-type chips and GeneChip.
The parametric framework, on the other hand, employs a strict model and normalization cannot be completed without coincidence between the model and chip data.
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