This method bypasses a number of challenges previously encountered in Pd-catalysed cross-coupling with organolithium compounds such as strict exclusion of moisture, dilution and slow addition.
This multi-center project conducted epidemiologically based recruitment of a large, demographically balanced sample across a wide age range, using strict exclusion factors and comprehensive clinical/behavioral measures.
We reach similar conclusions regarding the validity of the instruments under this more strict exclusion restriction.
Firstly, strict exclusion criteria may be imposed to sieve out waveforms with artefacts.
The strength of the present study lies in the strict exclusion criteria.
Also, strict exclusion criteria to limit external factors that influence iron metabolism were applied and strict definitions were used.
We applied strict exclusion criteria in order to minimize the effect of other factors on headache occurrence, e.g., craniotomy.
Both, chelator preparation and labeling procedure, were performed under strict exclusion of metals (plastic vessels and coated spatulas).
The strengths of our study include its prospective design and the strict exclusion criteria, which limited the bias observed in other studies [12, 13, 14].
We did, however, identify our patient samples from a wider institutional audit database of hip fracture patients with strict exclusion criteria in order to maintain a homogeneous sample.
First, to eliminate the influence of potential confounders that might interfere EPC counts, we applied very strict exclusion criteria and selectively enrolled matched controls.
