The theory of strict and nonstrict differential inequalities related to ODEs and hybrid differential equations is available in the literature (see [24, 25, 28, 29]).
The theory of strict and nonstrict differential inequalities related to the ODEs and hybrid differential equations is available in the literature (see [2, 12]).
Furthermore, they established some basic results concerning the strict and nonstrict differential inequalities.
No genes passed our initial strict criteria for differential expression between the different cortisol regimes, although a large number did in the comparisons to control.
A miRNA family was annotated as up- or down-regulated if it least one of the members was up- or down-regulated under a strict definition of differential expression.
We noted, that while many miRNA families had more than one member, we have not found a single family containing both up-and down-regulated miRNAs under the strict definition of differential expression.
In all, 20 miRNAs passed through a very strict filter for differential expression between benign naevi and primary or metastatic melanoma, and only 2, miR-203 and miR-205, passed through the same filter for differential expression between primary and metastatic melanoma.
All genomic clusters were dedicated to one of the expression modes, i.e. under strict definition of differential expression no miRNA genes were inversly expressed within one genomic cluster (see Additional file 6 for the list of miRNA genes in large genomic clusters and their associated genomic features).
In summary, a total of 2,881 probes representing the Arabidopsis leaf transcriptome met our strict definition of differential expression in response to DBM feeding in showing a significant (p[t-test] < 0.05) and more than twofold difference of transcript abundance between treatment and control for at least one time point.
