In contrast, D'Arcangelo et al. (1999) analyzed the effectiveness of 0.5, 1, 3 %, and 5 % NaOCl on facultative and strict anaerobic bacteria and showed that all concentrations had an antibacterial effect on all species tested.
Of the strict anaerobic bacteria that had a significant correlation with age, the majority exhibited a negative relationship and were detected in higher abundance in younger patients (Supplementary Table S3).
However, since P. gingivalis are strict anaerobic bacteria, they are not likely to proliferate in an aerobic environment such as that observed in the ILT (PO2 = 100 mm Hg).
Fermentation with strict anaerobic bacteria requires proper handling to maintain anaerobic conditions [ 39, 42].
They were thus considered as strict halophilic bacteria at neutral pH.
Difficult-to-treat microorganisms and strict anaerobic bacteria were more frequently isolated from patients without an early response compared to those with.
In strict intraamebal bacteria, we found Legionella-like amebal pathogens (7 ), Parachlamydia acanthamebae (8 ), and a giant virus resembling gram-positive cocci that we named mimivirus (9 ).
Extracts were less effective against C. albicans and exerted bactericidal effects at a concentration range of 0.07 5.00 mg mL−1 on strict anaerobic bacteria (Porphyromonas gingivalis, Prevotella intermedia, Fusobacterium nucleatum, and Parvimonas micra).
Genome shrinkage is therefore a fact in most if not all the strict intracellular bacteria and this process has been mostly accompanied by genome rearrangements and fast evolutionary rates of proteins.
