We aimed to investigate whether NIRS dynamic variables could reflect the magnitude of inflammatory process that follows strenuous exercise in marathon runners.
Doctors could not determine why the otherwise healthy and unusually fit young woman with no apparent risk factors — a devotee of yoga, strenuous hikes and marathons — had suffered strokes in the first place.
When going for a long strenuous exercise (ultra-marathon, endurance race, etc)., in addition to planning proper hydration and eating, bring along re-hydrant powder (Gastrolite or equivalent).
Training for a marathon requires strenuous exercise over the course of many weeks.
It has been shown in several studies that cardiac biomarkers are elevated after strenuous exercise such as marathon [ 9, 16- 18].
Plasma IL-6 concentration is increased after strenuous prolonged exercise such as marathon running [ 6- 9].
Following 2 hours and 30 minutes of strenuous cycling or running a marathon, the score drops to 50-60 (see Figure 2).
Combined with DNA fragmentation data, this is the first direct evidence that strenuous physical load endured during marathon provides a physiological protection against the proapoptotic process.
Although kidneys of the examined runners fully recovered within two days post-marathon, the study raises questions concerning potential long-term impacts of this strenuous activity at a time when marathons are increasing in popularity.
In humans, epidemiological studies assessing exercise and URTI have found that strenuous competitive exercise (e.g. marathon running) leads to an increased susceptibility to URTI [8], [9], whereas moderate training or physical activity can reduce the number of URTI symptoms [10], [11], [12].
