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We envision that targeted delivery of intracellular adhesive/signaling integrin-tTG complexes to lamellipodia should strengthen adhesion to the ECM at the leading edge of migrating cell and contribute to directionality of cell migration.
Integrins expressing on the cell surface mediate the interactions of neutrophils with endothelial cells and extracellular matrix (ECM) proteins to strengthen adhesion and migration for complete infiltration [ 21, 22].
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Exposure of cells to mechanical strain, fluid shear stress, or plating cells on substrates with varying elastic moduli activates integrins, which promote recruitment of scaffold and signaling proteins to strengthen adhesions and to transmit biochemical signals into the cell.
The crystal change from amorphous to crystal state intentionally by a conditioning process after compression enabled to increase tablet hardness by strengthening adhesion between particles.
The obtained plating coatings are crystalline with preferential orientation of (111), having advantages such as low-phosphorus content, high density, low-porosity, good corrosion resistance and strengthened adhesion.
The improved electrochemical performance can be attributed to the strengthening adhesion of the Si film to the cobalt nanomountain arrays and the formation of an island structure within the film, which provide good mechanical support and electron conducting pathway.
Using BN-covered Si wafers with a surface roughness on a 100 nm scale reduces the texture degree in the vicinity of the interface and strengthens adhesion of the pyrolytic carbon compared to the smooth Si substrate.
Clustering of cadherin contacts strengthens adhesion, while cadherin endocytosis is thought to weaken adhesion.
Interaction of E-cadherin with the catenins leads to clustering of E-cadherin thereby strengthening adhesion [6].
The reviewers found that the paper provides interesting data and interprets them in the framework of a neat scenario describing the maturation of contractile stress fibers and the role of a mechanosensitive VASP phosphorylation in strengthening adhesion complexes as they mature.
Vertebrate VEZT serves to link the cadherin catenin "core" to MYO7A, thereby strengthening adhesions (Küssel-Andermann et al., 2000), but it is also crucial for Listeria entry into epithelial cells (Sousa et al., 2004).
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CEO of Professional Science Editing for Scientists @ prosciediting.com