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In addition to being a common marker of activated fibroblasts, αSMA can enhance the mechanical strength of contractile actin bundles and can be sufficient to enhance fibroblastic contractile force 29.
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The configuration of CPC4 accounted for an increase/decrease in the strength of the contractile forces at front and back, and a decrease/increase of the contractile lateral forces at the sides of the cell.
The net physiological effect of aging on skeletal muscle is loss of strength and contractile function.
Pharmacological evidence is presented supporting the theory that the increase in contractile strength of isolated cardiac muscle under suprathreshold stimulation is due to the release of an adrenergic mediator (norepinephrine).
Thus, the contractile strength of CM-c was transmitted to the lens indirectly by the mediation of the zonule and associated ECM.
Interestingly, S. miltiorrhiza appears to have benefits in ischemic myocardium, enhancing the recovery of contractile force upon reoxygenation.
Denervation causes loss of contractile force and muscle atrophy.
From the displacement field we calculated the traction field, and from the traction field we computed a scalar measure of contractility called the contractile moment, T.[14] The contractile moment corresponds to the strength of an equivalent force dipole and provides thereby a scalar measure of the cell's contractile strength.
Reduced force generation without the loss of contractile protein in hypercapnic rats suggests posttranslational modifications of the contractile proteins.
Changes in muscle strength and contractile properties after 56 days of bed rest were assessed by means of linear regression, and expressed as a percentage change with respect to the value at BR4. One-sample t tests were used to determine whether the normalized slope (slope/intercept on y-axis) of the linear regression was significantly different from zero.
It has been also reported that Wnt7a treatment ameliorates muscular dystrophy, reducing the level of contractile damage and significantly increasing muscle strength of mdx mice (von Maltzahn et al., 2012).
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CEO of Professional Science Editing for Scientists @ prosciediting.com