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The European Medicines Agency requested a postlicensing cardiovascular safety study of febuxostat versus allopurinol, which has been named the Febuxostat versus Allopurinol Streamlined trial (FAST).
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New statistical designs such as futility analysis may improve and streamline trials in both adults and children.
A large streamlined safety trial is expected to have good external validity.
SCOT is an active comparator, streamlined clinical trial with a Prospective, Randomised, Open label, Blinded Endpoint evaluation (PROBE) design.
WHO also would create a Pandemic Product Development Committee, monitored by an independent board, to define priorities, streamline clinical trial designs, and help create stockpiles of vaccines.
Every region has appointed a person to coordinate and streamline clinical trial efficiencies.
Furthermore, such biomarkers would enhance the development of adaptive trial designs, something not currently possible in lupus nephritis trials, further streamlining the clinical trial process.
They include support for a heart-lung system that can test potential drugs and an effort to dramatically streamline clinical trials.
Ten of the world's largest pharmaceutical companies said on Wednesday that they would cooperate on research aimed at accelerating drug development, starting with streamlining clinical trials.
Duke's Eckstrand also streamlines clinical trials.
It grew out of a series of hearings and roundtables last year on ways to spur biomedical research innovation and streamline clinical trials and the drug approval process.
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