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The paper presents a general strategy applicable for sensitivity analysis (SA), and uncertainity quantification analysis (UA) of parameters related to a nuclear reactor design.
The strategy optimized for sensitivity should be applied in cases where retrieval of all relevant articles is key, and substantial weeding of irrelevant content is seen to be acceptable.
We propose a novel strategy for global sensitivity analysis of ordinary differential equations.
That is, it cannot otherwise be predicted whether the autophagy induced by radiation or chemotherapy is associated with resistance and the circumstances under which autophagy inhibition might be a useful strategy for enhancing sensitivity to therapy.
In the scenario analysis, the strategy where CTA is followed by DSA remained the least costly strategy for a sensitivity of determination of coiling within the range of 60 100%%.
Our results suggest that the optimal strategy for chemotherapy sensitivity prediction integrates molecular variables such as ER and HER2 status with corresponding microRNA and mRNA expression profiles.
These findings led to the examination of mTOR inhibition as a strategy for improving sensitivity to trastuzumab-based therapy [ 22].
These results also demonstrated that inactivation of Skp2 could be a promising strategy for restoring sensitivity to paclitaxel.
Targeting the PI3K/Akt 2 pathway might be a promising strategy for enhancing sensitivity to docetaxel in breast cancer [ 26].
Linear quadrupole ion trap (LTQ Orbitrap MS with full scan option provides the possibility for a mid-term untargeted strategy for high sensitivity, mass accuracy in low parts per million range [ 44], and a mass resolution of >100,000 (FWHM) [ 45].
We tested the MEDLINE search strategy for its sensitivity to retrieve a reference set of 48 records of reports of potentially eligible studies known to be indexed in MEDLINE that were identified by our preceding scoping review (Hollands 2013a).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com