But if you point to one person and say, He did it, the interest in all of those tangential strands is lost.
The earliest demonstration that Cdc13p functions in chromosome capping was the discovery that in cells with a temperature-sensitive cdc13 -1 allele incubated at elevated temperatures, telomeres are degraded in a strand-specific manner such that their C strands are lost for many kilobases (Garvik et al. 1995).
You may experience an increase in shedding, as old hair strands are lost to make room for new hair growth.
It would be a huge mistake for the NT, and theatre as a whole, if this programming strand is lost when the renamed Cottesloe reopens as the Dorfman.
Unwinding is accompanied by differential strand retention; one strand is retained by the Ago protein while the other strand is lost.
Duplex viRNAs are incorporated into the Argonaute protein RDE-1 and one strand is lost to give rise to primary viral siRNAs (primary viRNAs).
However, some did sink when killed 10-300% in the North Pacific) and were lost unless they later stranded or surfaced.
We have previously shown that QPM is elevated and that the leading-strand bias is lost in mutants lacking the major 3′ ssDNA exonucleases, ExoI and ExoVII.
The mapping orientation is thus informative, as opposed to regular RNA-seq experiments where the strand information is lost during the cDNA synthesis step.
Since massively parallel pyrosequencing is dependent on a fragmentation step, where the mRNA is randomly cut into processable pieces, the strand orientation is lost and thus the direction of transcription for the generated reads and, ultimately, for the assembled contigs [ 18].
