Sentence examples for strand tag from inspiring English sources

The ChIP-cor program generates a histogram indicating how many times a − strand tag is found at a particular distance of a + strand tag.

Let c i  + 51, …,  c i  + 68 be the Crick strand tag numbers in this region.

Each plus strand tag was attributed to the closest downstream predicted site if such a site occurred within 200 bp.

For the libraries that involved sonication procedure, the average ChIP fragment lengths were estimated using strand cross-correlation profiles as previously described and the forward and reverse strand tag locations were shifted accordingly.

In ChIP-seq experiments, + and − strand tags tend to occur in equivalent numbers in clusters around the transcription factor binding site.

The minus strand tags were attributed to the closest upstream predicted site applying the same distance constraint.

Genome-wide positional correlation between the plus and minus strand tags was made by assessing the frequency of minus tags at varying distances from the plus tags.

The SISSRS method is attractive because it explicitly makes use of information from the orientation of tags around a protein binding site - where it is expected that forward strand tags will be found upstream of the true binding site and reverse strand tags downstream.

Since ChIP-DNA fragments are equally likely to be sequenced from both ends, the tag density around a true binding site should show a bimodal enrichment pattern, with forward strand tags enriched upstream of binding sites and reverse strand tags enriched downstream of binding sites [ 10, 11, 35, 37].

Mapping of the polarity of tags surrounding NFI predicted sites revealed symmetrically distributed profiles of the plus and minus strand tags around the centers of the binding sequence dyad (see Additional file 1: Figure S5).

The larger spacing between plus and minus strand tags seen with STAT1 is consistent with the previous observation that STAT-1 can form dimers or trimers that occupy larger portions of the DNA [ 39, 40].