Exact(1)
The synthesis of genomic (49S) RNA, as well as a subgenomic (26S) mRNA that encodes the virus structural proteins, depends on the synthesis of a genomic-length minus strand copy.
Similar(59)
The single stranded bisulfite-treated nucleic acid may be labeled opposite 5-meC sites via primer extension in the presence of biotin-dGTP, or the strand may be converted to double-stranded material and this new strand copied using biotin-dCTP.
Replicative enzymes (RDRP) synthesize a negative-strand copy of the +RNA.
HCV RNA positive- and negative-strand copy numbers were determined in brain samples from all patients by a strand-specific reverse transcriptase with subsequent PCR amplification and interpreted from a standard curve.
A second copy of Rep protein catalyzes the cleavage of the newly formed DSO, effectively releasing a single stranded copy of the plasmid.
Smith being one of the writers who dreads the prospect of seeing the Strand review-copy tables festooned with his books bought 650 copies of one of his remaindered books and sent them to colleges, libraries and towns in the U.S. until he and the Strand had only two copies left.
Strand switching (copy-choice recombination) by reverse transcriptase could generate an undamaged copy of genomic DNA from two damaged ssRNA genome copies.
This process was originally discovered in E. coli: as the coding strand is copied into RNA (transcribed), DNA damage in that strand is mended at a higher rate than normal9.
There are writers who so dread the prospect of seeing the Strand review-copy tables festooned with their book that they avoid the place for weeks around publication day.
Some evolutionary biologists had suggested that if one strand was copied more faithfully, it would preserve genes, while extra mutations on the other strand might allow new and possibly advantageous features to spring up.
In the infected cell, the 49S genomic RNA serves both as mRNA for the translation of the nonstructural proteins and as a template for synthesis of full-length minus strand RNA copies [1].
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