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a General strand, b smart strand.
Nevertheless, the FN domains have an invariant tryptophan at the center of the β strand B in place of the cysteine in the Ig-like domain that assists to form a hydrophobic core to stabilize the FN domain.
In particular, lysine-glutamate salt bridges are most stabilizing when formed between residues in the middle strand (B) and the trailing strand (C), whereas lysine-aspartate salt bridges are most stabilizing when formed between residues in the leading (A) and middle (B) strand the latter observation being consistent with recent NMR data on a heterotrimeric model peptide.
Pair (7, 9) is located in the loop connecting strand d from one repeat to strand a in the next repeat for and pair (25, 27) in a β-turn linking strand b and c within a repeat (fig. 4a).
The top surface is formed by loops connecting strand D of one blade and strand A of the next (DA loops) and loops connecting strand B with strand C in the same blade (BC loops).
a Plus strand /minus strand b Negative values represent overlapping nucleotides.
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Heparin/sulfatide binding was restricted to IG5 and shown to depend on four arginine residues that are close in space in β strands B and E of the C-type IG fold.
Open image in new window Fig. 5 a stress state in the repair jacket along the shear crack for confining pressure from hybrid jacket and prestressing strands, b increase of shear deformations due to widening of shear cracks in an RC column with existing damage subjected to aftershock attacks.
For example, a high number of non-conservative mutations were found for group I in β-strand B, loop C–C' and β-strand C'.
The second sheet comprising strands B, C and D, is oriented roughly perpendicular to the first one, such that strands B and E are proximal (Figure 1B).
It assign α helix (H), β-strand (E and e), isolated β-strand (B and b) 310 helix (G and g), π-helix (I), coil (O, coded as '-' in this database) and PPII (P and p).
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