Some bacterial strains from the same species (E. coli 1) were found sensitive to these particles whereas others were highly resistant to silver nanoparticles (E. coli 2).
As a matter of fact, it was able to distinguish L. monocytogenes obtained from different species of animals, different food samples and strains from the same production plant isolated in different periods of the year.
For evaluating the efficacy of these nanoparticles against different strains of the same species, we have also examined the antibacterial activities of these nanoparticles against different strains from the same species.
This difference in the antibacterial activity of silver nanoparticles for different bacterial strains from the same species may be due to the genome islands that are acquired through horizontal gene transfer (HGT).
Moreover, in case of some strains from the same species, not only different bactericidal potential of Ag NPs was observed but also some strains were totally resistant against these Ag NPs, at least under the given experimental conditions.
Various bacterial strains from the same species were further tested for their response to Ag NPs, and the results were compared based on the MIC (minimum inhibitory concentration) of silver nanoparticles.
These observations were consistently made in reproducibility experiment and for the two strains from the same species.
Interestingly, a comparison of SC84 with 05ZYH33, both strains from the same outbreak, identified 2602 SNPs, 596 insertions, and 304 deletions.
A dendrogram based on group column means clustered the groups according to clade (Supplemental Figure S3), which suggested that strains from the same clade had similar transcriptional profiles.
All but two clinical E13 strains were isolated between 2000 and 2002, and clustered in one distinct group together with European and Asian strains from the same period.
Here we describe whole genome sequences of three S. suis strains from the same lineage: one from European pigs, and two from human cases from China and Vietnam.
