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This could be achieved, for example, using the Sigma1278b strain strategy mentioned by Reviewer #2.
SLR0054 animals were initially constructed to expedite screening, however the Dpy phenotype of unbalanced worms made screening difficult and so the two strain strategy described above was eventually employed.
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Even if the development of recombinant seed strains by reverse genetics becomes standard over the next few years, questions remain about how effective the current formaldehyde-inactivated seed strain strategies would be against pandemic strains, particularly the currently circulating H5N1 strains.
This review covers enzyme systems involved in CBP, potential wild-type CBP strains, strategies for engineering a CBP strain or consortium, as well as major barriers for conducting CBP.
The long-term competition of strains (strategies) with selective values dependent on their frequency in the population could be an important source of species cohesion even in asexual species.
By integrating the existing strain-design algorithms with dFBA, we have developed a novel strain-design strategy called Dynamic Strain Scanning Optimization (DySScO).
Since our goal was to demonstrate the necessity and effectivness of a dynamic strain design strategy, we simplified the problem by adopting an idealized feeding strategy in which the glucose concentration is maintained at a high level (20mM) until the reactor becomes full.
So a rational strain improvement strategy was developed to tune the unbalanced spinosyn biosynthetic pathway.
These results demonstrate that our strain engineering strategy allows efficient l-lysine production independent of the oxidative pentose phosphate pathway.
One consideration in our strain design strategy was to test our hypothesis that immune responses induced to protective antigens will be superior in RpoS+ S. Typhi strains.
The present study provides a new strain improvement strategy for A. sojae to further explore its potential as pectinase biofactory.
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