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This is a reasonable approach which in our tool can be achieved by setting a negative value for the strain conservation score and it is also one of the functions available at PGAT.
We estimated the evolutionary conservation of proteins among different strains of the same species using the following score: 2 where S C p is the strain conservation score for protein p, computed by adding the highest NS value (max (N S p )) obtained against each other strain (j) of the selected species in the data set, with m the total number of distinct strains of the particular species.
Similar(58)
The high inter-strain conservation and the stability of the 47-kb SSR reflect its ancient acquisition.
Criterion for progressive cracking in the coating layer was established in sense of strain energy conservation, and the crack density is thereby estimated.
To address this issue, here we establish a coarse-grained molecular dynamics (CG-MD) model of graphene using a strain energy conservation approach.
The CG potentials for nanotubes and polymer chains are calibrated using the strain energy conservation between CG models and full atomistic systems.
Three situation can occur: (i) a single hit (or no hit) in each strain, with conservation of synteny on the genome; (ii) a single hit (or no hit) in each strain, but with a breach of synteny for at least one of the homologous genes; (iii) multiple hits (two or more for at least one strain) in different strains.
The generation of C57Bl/6 and DBA/2J collagen X Tg and KO congenic strains revealed conservation of all the characteristic disease phenotypes observed in the outbred collagen X Tg and KO mice, thus excluding the contribution of strain specific modifiers to the disease phenotype.
The two O1-type strains, RB50 and D445, are similar to the four O2 strains in their conservation of the 14 genes from wbmA through wbmN, but contain a very different set of genes within what we have designated Variable Region A (VRA) that correlates with their antigenically distinct O1 type (wbmO-wbmZ).
The human MPV17 gene can complement sym1Δ deletion strains, indicating functional conservation (Trott and Morano, 2004).
Comparisons of the putative ori region among related Wolbachia strains showed higher conservation of bases within binding sites.
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