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We use a simple word-based motif model and a straightforward score of pairwise sequence similarity as an alignment-free and efficient means to look for similar regulatory sequences, without relying on orthologous sequences or an explicit requirement of motif overrepresentation.
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It was developed by a team of psychiatrists in conjunction with the World Health Organization, and it is used by many clinicians to diagnose A.D.H.D. The test is simple and has a straightforward scoring system.
Promoters were localized using a straightforward scoring strategy that was formulated to identify similar motifs.
We felt that a relatively straightforward scoring system would make the collection and interpretation of information relatively efficient.
Based on this property, we derived a straightforward scoring system based on the numbers of common motifs uncovered to support whether the finding is statistically significant.
Thus, a straightforward scoring function would summarize the similarity of gene j to all hits of the screen k (Formula 2.1).
Benefits included ease of administration of the tests, low cost of administration, and straightforward scoring – all very useful in the context of developing countries (4).
Previous studies have reported the many advantages of the NRS, including ease of administration, straightforward scoring mechanism, patient preference, and ability to be used in parametric analyses [ 15, 21, 44, 45].
While the odds ratios (coefficients) from the multivariate regression analysis can be used to estimate the probability of an event (in this case ureteral stone), we sought to construct a more straightforward scoring system for clinical use without the use of complicated calculations.
The EQ has a forced choice format, can be self-administered, and is straightforward to score because it does not depend on any interpretation.
In this sense, residuals capture individual deviations from a hypothetical, average control, thereby providing a straightforward abnormality score to measure the size of individual CP participants' deficit.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com