Sentence examples for straightforward marker from inspiring English sources

The apparent decline in seroprevalence observed around the age of 25 years suggests that seroprevalence is not a straightforward marker of all past HPV infection.

Assays to measure γH2AX are reasonably well developed and are currently being tested clinically with different cancer therapeutics and may therefor prove a relatively straightforward marker to include in clinical studies [ 36- 38].

In the long term, the lack of a straightforward marker for identifying the PINA-null allele leads us to develop a Pina-N1 marker for detection of Pina-D1b allele [ 29].

It is therefore easiest to perform intervention trials in patients that have been newly diagnosed with T1D as they already carry a straightforward marker of the disease (hyperglycaemia), are certainly highly motivated and the disease course is still amenable to modulation [ 18].

The power calculation was conducted following a simulation scheme as described by Wang et al. [ 14], assuming (i) a set of five straightforward markers of clinical benefit were present (with an area under the curve of 90%) and (ii) that 25% of patients would derive clinical benefit from erlotinib.

We also analyzed these data with a straightforward single-marker method to select the most robust loci for candidate gene hypothesis testing.

Interestingly, we found a significant inverse correlation between α-synuclein and LC3-II levels (r=−0.55, P<0.0001, Figure 4c), suggesting the possibility to use α-synuclein as straightforward autophagy-related marker in T lymphocytes and immunopathology studies.

First the allele originating from each parent was determined for the straightforward cases of markers that were homozygous or heterozygous with at least one parent homozygous.

Clinical validation for prognostic markers is more straightforward, as only the clinical outcomes between marker-positive and marker-negative patients are compared within a cohort of uniformly treated patients.

This straightforward integration will improve marker performance in association and QTL mapping studies.

A haploid model is assumed for simplicity of notation, but the extension to two alleles per marker is straightforward.