Estimating internal exposure or dose of dioxins and related chemicals such as dibenzofurans and dioxinlike polychlorinated biphenyls is relatively straightforward in laboratory animals because a known dose is given and the amount absorbed can be measured.
Although HI is straightforward, most laboratories preferred their own assays.
Discrimination of coding and non-coding transcripts is not straightforward, and different laboratories are using different methods.
However, because of two special features analysis of fission yeast cell growth by flow cytometry is not straightforward: First, under standard laboratory conditions the cytokinesis of fission yeast cells occurs at the end of S phase and for that reason cells in G1 and S phase are binuclear (Fig. 1).
The experimental data are fairly straightforward to obtain by standard laboratory methods, and the computer program is executable on a personal computer.
The GoldenGate TALEN assembly kit by Cermak et al. is publicly available, straightforward to establish in the laboratory, reliable, as well as time and cost-efficient [ 13].
Our data indicate that one of the most important steps in viral detection by deep sequencing may be the removal of host genomic DNA by post-extraction treatment with DNase – a relatively straightforward procedure for most clinical laboratories.
To achieve a "formalin-free laboratory" we tested straightforward-to-make fixatives along with registered reagents offered as formalin substitutes.
In particular, we sought to create a simple and straightforward method that enables unspecialized laboratories to engineer custom DNA-modifying proteins using only defined modular components, a web-based utility, and standard recombinant DNA technology.
Developed tools must, therefore, be general enough so that they can be used between laboratories and also straightforward to customize so that wet-lab biologists with a bit of training in programming can deploy and maintain the software.
