Amongst all of the pulmonary cytokines and chemokines examined, peak levels of pulmonary IL-17 that occurred on day 7 of infection provided the most straightforward potential correlate of protection.
Second, it is more straightforward to correlate patterns of gene expression with the observed histologic changes that occur over time.
In such a system where the film-coupled NPs are all separated from the underlying continuous film by a uniform separation distance, it is straightforward to correlate shifts in the coupled NP film LSPR to changes in the NP film separation distance using a similar approach to our previous reports on NP film PNRs.
We show that our system provides a straightforward way to correlate phenotype and genotype and is potentially amenable to biochemical optimization in ways that the in vivo system cannot achieve.
A straightforward expression to correlate head and flow rate correction factors due to viscosity follows from the present approach, thus yielding a useful tool that might help in proposing a general method to estimate performance degradation.
Further, the adaptive significance of a shorter recovery time is not always straightforward, although it correlates with differences in the thermal niche occupied [50] as well as geographical variation in cold stress resistance, e.g. [31], [51] [52].
The correlation between elevated XIAP levels and clinical outcome, however, is not straightforward since its overexpression correlates with disease severity in acute myeloid leukaemia but not in lung cancer or prostate cancer [ 17, 18].
We find that the predicted ON- and OFF-pathway responses do not correlate in a straightforward manner with the psychophysical thresholds, suggesting that detection of increment and decrement probes may not be performed exclusively by one pathway.
Indeed, despite the appealing simplicity of the idea, it is not obvious that there should be simple measurable parameters, such as asexual parasite density, defining parasite virulence or that these should correlate in a straightforward manner with transmission; this has been discussed in depth for the case Neisseria, as noted in the Background section [ 11, 12].
