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At the biochemical level, Lat have a straightforward and specific mode of action, which end up in a complete shift from filamentous actin (F-actin) to globular actin (G-actin) by forming G-actin-Lat complexes [ 12].
This tendency could be due to the relatively straightforward and specific nature of their work: it has a clear outcome that is often positive (as opposed, for instance, to managing a chronic disease).
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The guidelines for the initiatives at Cortex and Perspectives are straightforward, and while specific kinds of studies will require specific solutions, the general principle is widely applicable.
The study shows that the coating of a metallic substrate by a catalyst is not straightforward and requires specific studies dealing with both chemistry (chemical affinity between substrate and catalytic layers) and catalytic engineering (catalytic performance in taylor-made reactors).
These tasks are not particularly straightforward, and very often specific photogrammetry knowledge is required.
cDNA probes are easy to generate by PCR, while printing on nylon membranes is more straightforward and requires less specific equipment than, for example, on glass chips.
Although bioinformatics tools for computational analysis have developed rapidly [55]– [57], the choice of analysis is not straightforward and depends on the specific aims and study design.
The use of evidence in Mozambique was fairly straightforward and aimed at answering specific policy-relevant questions, such as a project piloting zinc for diarrhoea treatment.
In general, PCR is known as a sensitive, specific, straightforward and fast tool for pathogen detection and several conventional PCR tests have been proposed to detect MmmSC [ 2, 9, 10, 27- 29].
In the first and most straightforward model, specific intracellular parts of the channel are attracted towards the plasma membrane due to the direct interaction with PI 4,5 P2, leading to a stabilization of the open state.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com