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The collection and storage of serum samples are easy, the immediate and delayed testing are both equally feasible making emergency analyses as well as prospective and retrospective studies possible.
However, after 12 months of storage of serum at −80°C, there were three discordant results.
Screw-cap cryovials work well for storage of serum or urine.
Blood was drawn, primarily for the HIV test, but also for storage of serum and leukocytes.
Storage of serum samples is unlikely to have biased study results, as all samples were similarly stored.
In this series, mutation detection was not found to be significantly affected by 6 months of storage of serum samples.
Similar(45)
The effect of prolonged storage on serum antioxidant samples was addressed within the Multiple Risk Factor Intervention Trial (MRFIT); no appreciable degradation was seen in samples stored at −50 to −70°C (15).
Blood collection, processing and storage of the serum samples was performed under strictly defined conditions which were the same for cases and controls.
Informed consent for the collection and storage of their serum and peripheral blood mononuclear cells (PBMCs) was obtained from all subjects.
The CMV IgG levels did not appear to be affected by the duration of storage of the serum samples and no significant correlations between CMV IgG or EBV IgG level and duration of storage were found.
The concentration of beta-carotene was measured in the stored serum samples from 271 men who were subsequently notified as having cancer and from 533 unaffected controls, matched for age, smoking history and duration of storage of the serum samples.
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