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Chen et al. also show that a chemical compound that stops the function of the Neu1 enzyme prevents the toll-like receptors and hence the immune cells from becoming overly activated.
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Bisphosphonate is widely used in the treatment of osteoporosis and osseous metastasis of cancer, and it is known to play a role of reducing bone loss by reducing or stopping the function of osteoclast [8, 9].
The inhibitory KIRs recognize distinct HLA class I molecules and stop the effector function of NK cells, thus offering protections to healthy cells.
I would have to take four weeks of fertility drugs that would first stop the normal functioning of my system, then overstimulate my ovaries.
Last week an amendment was moved successfully by Labour peer Norman Warner to the cities and local government devolution bill which stops the transfer of NHS regulatory functions held by national bodies.
To examine how premature stop mutations may affect the function of seipin, we generated constructs in which the E113X, R138X, R275X and Q391X pathogenic mutations [ 2, 3, 21] were introduced by site-directed mutagenesis into the full-length cDNA encoding the long form of seipin bearing an N-terminal triple-FLAG tandand a C-terminal Myc tag.
But her view of emotional life and the function of psychotherapy stops well short of the idea essential to psychoanalysis that there is a dimension of the human mind that is hidden from conscious thought.
Almost 80% of the Alu exons in our RNA-seq data are predicted to introduce frameshifts or stop codons that will strongly impair the function of the 1,572 genes containing them.
Exonic SNVs such as missense mutations resulting in amino acid substitutions and nonsense mutations introducing new stop codons can seriously disrupt the function of human protein-coding genes.
Further 23 SNPs in coding sequence that introduced a TAG, TAA, or TGA stop codon could potentially alter the function of these genes.
The stress of exercise can stop the gonadal function, by the production of glucocorticoids and cathecholamines with activation of the corticotropin releasing hormone neurons.
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