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An aging process that has as participant a cell after a cell has stopped dividing.
Most cells have already stopped dividing in the run-up to reproduction.
Cell aging may occur when a cell has temporarily stopped dividing through cell cycle arrest (GO 0007050) or when a cell has permanently stopped dividing, in which case it is undergoing cellular senescence (GO 0090398).
When the researchers blocked PRMT5 in tumor cells, they found that the cells stopped dividing and entered a dormant, nondividing state.
Neurons have many features that might make them particularly vulnerable to gencDNAs: they are long-lived, have mostly stopped dividing, and have higher levels of reverse transcriptase activity and DNA-strand breaks than do non-neuronal cells8.
This year, Jeff Bezos joined investors who put $127 million behind Unity, a startup in San Francisco that's developing drugs to zap older, "senescent" cells that have stopped dividing.
Similar(11)
Can we stop dividing ourselves?
"We have got to stop dividing American voters..
"We have got to stop dividing the American voters.
Either the cells shed by the tumor are killed, or they stop dividing, becoming dormant.
A cancerous cell, after al, is a cell that will not stop dividing.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com