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The big questions asked by "The Interestings" are about what happened to the world (when, Jules wonders, did "analyst" stop denoting Freud and start referring to finance?) and what happened to all that budding teenage talent.
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STOP denotes a strong transcriptional termination signal, removable by loxP recombination.
This mutation results in the creation of a premature stop codon (denoted by "asterisk" in Fig. 1 A) resulting in elimination of the transcript.
In addition, we examined whether the TPAs contain a protein domain of known three-dimensional structure, that is disabled by a frameshift or a premature stop codon (denoted 'TPA DD s'; see Methods for details of annotation of such domains).
We further extracted protein sequences that contain asterisks denoting stop codons and more than fifty-four AA long to perform the C0 to C50 searches ('dataset_2' in Additional file 1).
We also computed the number of stop codons (TAA, TAG, TGA that we denoted STOP) and the product of the relative frequencies of C, G and A, i.e. P C(1) P G(2) P A(3), over all frames.
Table 4 Percent of pauses events denoting full stops and commas for each speaker (P presentations/orations, T translation, R radio interviews) Full stops Commas Recordings n_p.
The stopping distance of a linear block code, denoted as s(H), is defined as the set of least cardinality among all stopping sets of code.
Some letters are neither: for example, the letter denoting the glottal stop,, has the form of a dotless question mark, and derives originally from an apostrophe.
"ACs Run (stop RTM at 6)" denotes that we manually stop RTM when txRate≥6.
No one ever stops for pedestrians, even though there are markers denoting pedestrian crossings and yellow warnings.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com