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ART-related knowledge was generated using a combination of three questions: knowledge of recent CD4 count, and correct responses to two questions, do you stop ART when weight improves, and does ART cure HIV/AIDS.
But unlike the Impressionists or the Cubists the Pre-Raphaelites did not stop art in its tracks, even if they were admired by Picasso during his Blue Period, Salvador Dalí and Wassily Kandinsky.
Director Alex Meillier extols "the power of ordinary individuals to change the world", while Singaporean Anthony Chen says: "Filmmakers are very good at working within limits and working within restrictions – Iran is one of the most restrictive countries in the world, but it's produced some of the most subversive and most interesting cinema – nothing can stop art".
Our findings confirmed that these patients interrupted ART for temporary obstacles and most of them never intended to ultimately stop ART.
Counsellors also did not consistently address the practical issues of taking ART, such as advising patients not to share medication with other patients and to not start or stop ART without consulting a clinician.
While the mechanism of latent virus clearance has not been defined, in the first of these, the Berlin patient Timothy Brown, did stop ART, but as pointed out by the author, underwent two CCR5-deficient stem-cell transplants that could through a combination of resistant cells and graft versus host reaction have cleared residual latent cells.
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Patients found alive were further categorized as on ART, transferred out to another ART program or having stopped ART.
While the success of the ART scale-up has been well documented globally, attrition (death, lost to follow-up [LTFU], and stopping ART) among patients in care remains a major programmatic challenge (3, 4).
In addition, we identified subjects who changed clinic site, stopped ART, died or were lost to follow up.
The outcomes were either death, stopping ART or LFU within the first 12 months, while for patients alive and on ART follow-up was censored at 12 months.
In contrast, ART-responding polyICLC/AT-2 SIV vaccinated animals had significantly smaller viral rebounds and all peaked at <3×103 RNA copies/ml 3 weeks after stopping ART (Fig. 1B).
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