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Seventy patients (36 %) had experienced 2 4 clinical stone events, 41 (21 %) had suffered 5 10 events and 844343 %) more than 10 stone events.
Spearman's correlation coefficient was used to correlate the number of clinical stone events with measures of kidney function.
The number of clinical stone events and/or surgical stone removal procedures did not correlate with either SCr or eGFR.
Seventy patients (36 %) had experienced 2 4 clinical stone events, 41 (21 %) 5 10 episodes and 844343 %) more than 10.
Interestingly, no correlation was observed between the number of stone events and/or surgical stone removal procedures and kidney function in our study.
We speculate that disease severity may have contributed to the increased CKD risk in our study since a large proportion of the cases had a history of both multiple stone events and stone removal procedures.
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The system forms part of a platform that aims to predict a urolithiasis (urinary stone) event where qualitative measures of K+, Ca2+, Cl− and Na+ concentrations in urine can be obtained through impedance/ conductivity.
Finally, the definition of a clinical stone event as acute flank pain associated with hematuria without confirmation by imaging can be considered a limitation.
In cases where a clinical stone event was not confirmed by imaging, urinary tract infection as a cause of acute flank pain was excluded.
Two patients who only had a single SCr value available obtained during an acute stone event were excluded from the kidney function analysis along with their corresponding controls.
A clinical stone event was defined as either acute flank pain associated with hematuria and/or the detection of a stone by a medical imaging study, or a patient-reported stone passage.
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