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The system forms part of a platform that aims to predict a urolithiasis (urinary stone) event where qualitative measures of K+, Ca2+, Cl− and Na+ concentrations in urine can be obtained through impedance/ conductivity.
In cases where a clinical stone event was not confirmed by imaging, urinary tract infection as a cause of acute flank pain was excluded.
Finally, the definition of a clinical stone event as acute flank pain associated with hematuria without confirmation by imaging can be considered a limitation.
Two patients who only had a single SCr value available obtained during an acute stone event were excluded from the kidney function analysis along with their corresponding controls.
A clinical stone event was defined as either acute flank pain associated with hematuria and/or the detection of a stone by a medical imaging study, or a patient-reported stone passage.
The eGFR was calculated by the MDRD study equation using the lowest available SCr value within the last year of observation or SCr measured at least 3 months after a documented clinical stone event.
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Seventy patients (36 %) had experienced 2 4 clinical stone events, 41 (21 %) had suffered 5 10 events and 844343 %) more than 10 stone events.
The number of clinical stone events and/or surgical stone removal procedures did not correlate with either SCr or eGFR.
Seventy patients (36 %) had experienced 2 4 clinical stone events, 41 (21 %) 5 10 episodes and 844343 %) more than 10.
Spearman's correlation coefficient was used to correlate the number of clinical stone events with measures of kidney function.
Interestingly, no correlation was observed between the number of stone events and/or surgical stone removal procedures and kidney function in our study.
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