Exact(2)
Therefore, we propose a RCM based on stochastic principle to understand the traffic behavior in a better way.
Simulation studies of XCI, based on a stochastic principle, indicate that XCI counting and choice can be mimicked when using a probability for an X chromosome to be inactivated, in which the probability is dependent on a nuclear XCI-activator concentration acting at differential threshold levels for X chromosomes with specific Xce alleles.
Similar(58)
We propose a novel metric known as rate control metric (RCM), formulated through stochastic principles.
It is therefore likely that stochastic principles broadly underlie the individual variations commonly observed in inbred mouse models of disease.
These ideas are correct if two unspoken assumptions are fulfilled: first, that the diversity of chemicals which make up human exposures act in strictly independent ways, according to the stochastic principles of the mixture concept of independent action [ 8].
We are now in a position to examine the two tacit assumptions that underlie this statement, namely that ADI or similar health-based guidance values generally represent zero effect levels, and that the diversity of chemicals which make up human exposures act in strictly independent ways, according to the stochastic principles of the mixture concept of independent action.
Recent lineage tracing has established that mouse IFE can be temporarily reconstituted from bulge stem cells (Ito et al., 2005; Levy et al., 2007) but is maintained by actively cycling cells that divide or differentiate according to stochastic principles (Clayton et al., 2007).
Even if we assume that the mixture assessment concept of independent action is applicable to the multitude of chemicals relevant to human exposures, certain risks may arise from small effects associated with single chemicals which might cumulate according to stochastic principles.
By the stochastic maximum principle and Ekeland's variational principle, we establish necessary conditions for a control to be near-optimal.
Then a stochastic maximum principle is obtained by virtue of Ekeland's variational principle.
Modern presentations of stochastic maximum principle with backward stochastic differential equations are considered in [21 23].
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