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Several other mechanisms have been proposed, including central medullary mechanisms, that involve altered stimulus response function of second-order transmission neurons in the spinal cord or in the brain stem; and central cortical mechanisms that involved disturbance of limbic pathways to the brain stem and caused by dysregulated endogenous pain-control system [4, 7].
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We also suggest functional forms, such as on/off switches and stimulus response functions to model transcriptional dynamics and present results of fitting these to experimental data.
Healthy controls demonstrated lack of a significant change in all parameters of stimulus response functions to acid, regardless of condition.
The activation function, F, represents the dependence of the stimulation response function (SRF), z, on the stimuli and inhibitors.
The similarity of the long-term steady state equilibrium we define in humans and the post-stimulus response functions strongly argues in favor of a common melanopsin-driven origin.
Since low-threshold mechano-receptors have recently been implicated in pruriception we aimed to characterize the peripheral primary afferent subpopulation conveying electrically evoked itch in humans (50 Hz stimulation, 100 μs square pulses, stimulus-response function to graded stimulus intensity).
Here, we characterize the stimulus-response function of auditory neurons using a generalized linear model (GLM).
Divisive attenuation would indeed be the type of effect primarily expected from the compressive stimulus-response function of retinal cones.
To identify the nature of the stimuli that trigger individuals' decisions to follow we characterized the stimulus-response function at the individual scale for all naïve individuals.
We quantified the individual stimulus-response function by the probability per unit time to depart (or departure rate, expressed in s−1) when exposed to such combinations.
Here, we propose an approach for characterizing the stimulus-response function of auditory neurons based on a generalized linear model (GLM).
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