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Note that the mouse returns to a quiescent state almost immediately after stimulus offset.
Remarkably, multisensory stimulation triggered rapid phase-locking mainly of excitatory hub activity persisting for seconds after the stimulus offset.
It allows Conley and Dupor to calculate how much the stimulus offset that budget loss, and see what effect this offset had on employment.
Data recorded during the associative learning (encoding) phase was epoched into trials starting 500 ms before stimulus onset and lasting until 1500 ms after stimulus offset.
The first (∼250- to 350-ms poststimulus onset) was during stimulus presentation, and the second (∼550- to 900-ms poststimulus onset) occurred after stimulus offset.
All these are factors that Conley and Dupor argue influence the amount of stimulus a state received, or the size of its budget hole, and thus they all also influence the degree to which the stimulus offset a state's budget shortfall.
In 69% of these neurons, the initial sensory responses to stimulus offset were followed for up to 700 ms by reverberant trains of bursting discharge, alternating in 100-ms cycles with inhibition.
Maximal [Ca2+]i was observed about 1.2 s after stimulus offset.
In their study the cumulative information continued to increase after stimulus offset.
The mean time delay with respect to the stimulus offset was 27.6 ms (Figure 9).
At stimulus offset, the full black disks replaced the notched disks and remained on screen until the next stimulus onset.
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