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Several in vitro studies have indicated that activation of ErbB receptors is a potent stimulus for survival, proliferation, migration, and invasion of PCa cells.
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This suggests that monocytes recruited to a site of inflammation receive stimuli allowing for survival through activation.
Collectively, the data demonstrate that CLL cells with high-risk features are in fact those that are most exquisitely dependent on microenvironmental stimuli for their survival and proliferation.
Perception of variations in environmental as well as internal developmental cues, transduction and amplification of signals and activation of the response to stimuli is crucial for survival, optimal growth and development.
Together with the results of the HER receptor quantitation, these findings indicate that ER activity provides a survival stimulus for LR BT474 cells in the early phase of their acquired resistance; however, with more prolonged L treatment, levels of HER2, HER3, and multiple HER ligands increase, and the HER pathway once again becomes the dominant driver of proliferation and survival.
Although rewards are physical stimuli and objects, their value for survival and reproduction is subjective.
From a teleological standpoint, it has been argued that animals benefit from chemosensory mechanisms that emphasize the animal's attention to stimuli that are "presumed" significant for survival and reproductive fitness (e.g., the odor/taste of foods eaten by their mother) [ 6].
For memory consolidation to be adaptive, information that is critical for survival, such as stimuli with an emotional or rewarding value, should be consolidated in priority during sleep (Perogamvros and Schwartz, 2012; Sterpenich et al., 2009).
Responding to noxious stimuli by invoking an appropriate escape response is critical for survival of an organism.
But the embattled Republican minority feels that its only chance for survival is to wish failure on the stimulus, the rescue, the bailout, and Obama's administration in general.
Plants sense and respond to external stimuli using a repertoire of mechanisms that regulate gene expression for survival in hostile environments.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com