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Daily sessions consisted of 10-min stimulation at 60% maximum stimulator output.
In some patients, the threshold was either very high or could not be determined; here, magnetic stimulation at the maximum stimulator output was used.
The mean motor threshold (RMT) was 53.3% (SD 7.15) of the maximum stimulator output intensity; hence mean stimulation intensity for the experiment was 63.9% (SD 8.62).
Resting motor threshold (RMT) was determined using a staircase method and was defined as the lowest stimulation intensity (% of maximum stimulator output) evoking a clearly discernable MEP in four of eight consecutive stimuli.
Resting motor threshold (RMT) was determined using a staircase method and was defined as the lowest stimulation intensity (percentage of maximum stimulator output) evoking a MEP >50 μV in at least four of eight consecutive stimuli.
Since our objective was to model altered activation rather than induce tissue damage [ 21], we limited the stimulator output to approximately twice the stimulating threshold (mean stimulator output was 0.366 ± 0.011 mA).
However, studies employing the CBI indicate a relatively strong stimulus (up to 80% of maximal stimulator output) is required to effectively stimulate the cerebellum [6].
This procedure resulted in stimulation intensities of 48 61% of maximum stimulator output.
The average stimulation intensity was 63.25% of maximum stimulator output (range 58%66%%).
Stimulation started at suprathreshold intensity (about 60% of stimulator output) and was decreased in steps of 1 2% of the stimulator output [46].
In all subjects, stimulation intensity was set at 70%% of the maximal stimulator output, corresponding to the mean intensity used in Exp1M1right and Exp2M1left.
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