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For the comparison of the different stimulation types, the sonograms of the non-stimulated glands served as the reference standard.
We predefined acupuncture as penetrating needling on acupuncture points, regardless of acupuncture methods or stimulation types; non-penetrative interventions such as acupressure, transcutaneous electrical nerve stimulator (TENS) or laser acupuncture were therefore excluded but reported separately for future research (see online supplementary appendix S2).
Figure 4 Distribution of the absorbed dose per administered activity for the different stimulation types.
Duplex sonography images were acquired for the submandibular glands under three different stimulation types (Figure 1).
Figure 1 Duplex sonograms of the salivary glands under different stimulation types.
All stimulation types were designed with equal pulse width, current intensity and mean frequency of stimulation (60 Hz), standardizing net charge transfer.
Similar(49)
The present 124I PET/CT study further explored the radioiodine uptake mechanism of the salivary glands using another stimulation type.
However, the reasons for variability are not only the dose but also the side, location of stimulation, type of coil and the number of sessions.
Due to the difference in the side, location of stimulation, type of coil and the number of sessions, the efficacy of magnetic signal on electrical activity of cerebral cortex is different.
Given that, future well-designed RCTs are needed to confirm which dose, side, and location of stimulation, type of coil or the number of sessions is more effective for migraine.
However, in our set-up of continuous TGF-β1 stimulation type I collagen mRNA did not alter.
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